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Proteintech
EIF4H Polyclonal Antibody
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Product Details
11012-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EIF4H Fusion Protein Ag1468 (1-188 aa encoded by BC010021)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
EIF4H has two isoforms. The short isoform (~25kDa) is the predominant isoform and is expressed alone in liver and skeletal muscle. This is a rabbit anti-EIF4H polyclonal antibody raised against part of N-terminal chain of human EIF4H, and can recognize both isoforms.
Immunogen sequence: MADFDTYDD RAYSSFGGGR GSRGSAGGHG SRSQKELPTE PPYTAYVGNL PFNTVQGDID AIFKDLSIRS VRLVRDKDTD KFKGFCYVEF DEVDSLKEAL TYDGALLGDR SLRVDIAEGR KQDKGGFGFR KGGPDDRGFR DDFLGGRGGS RPGDRRTGPP MGSRFRDGPP LRGSNMDFRE PTEEERAQR (1-188 aa encoded by BC010021 )
Target Information
This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: eIF-4H; Eukaryotic translation initiation factor 4H; Williams-Beuren syndrome chromosomal region 1 protein; Williams-Beuren syndrome chromosome region 1
Gene Aliases: eIF-4H; EIF4H; KIAA0038; WBSCR1; WSCR1
UniProt ID: (Human) Q15056
Entrez Gene ID: (Human) 7458
nucleotide binding
RNA binding
translation initiation factor activity
helicase activity
protein binding
translation factor activity, RNA binding
RNA strand annealing activity
RNA strand-exchange activity
ribosomal small subunit binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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