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Invitrogen
EKLF Polyclonal Antibody
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FIGURE: 1 / 1
EKLF Antibody (PA5-86441) in WB
Western blot analysis of EKLF in Lane 1: C6 whole cell lysate (40 µg), Lane 2: SP2/0 whole cell lysate (40 µg), Lane 3: MCF-7 whole cell lysate (40 µg), Lane 4: K562 whole cell lysate (40 µg). Sample was incubated with EKLF polyclonal antibody (Product # PA5-86441) using a 1:500 dilution.
Product Details
PA5-86441
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 288-335 of Human EKLF.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2803219
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
KLF1 is a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant Inblood phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EKLF; Erythroid krueppel-like transcription factor; erythroid Kruppel-like factor; erythroid transcription factor; erythroid-specific transcription factor EKLF; Krueppel-like factor 1; Kruppel-like factor 1 (erythroid); monoclonal antibody A3D8; neonatal anemia; truncated EKLF; truncated erythroid Kruppel-like factor 1
Gene Aliases: CDAN4; EKLF; HBFQTL6; INLU; KLF1; Nan
UniProt ID: (Human) Q13351
Entrez Gene ID: (Human) 10661, (Rat) 304666, (Mouse) 16596
in utero embryonic development
liver development
chromatin remodeling
erythrocyte differentiation
embryonic hemopoiesis
erythrocyte maturation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
erythrocyte development
cellular response to peptide
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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