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Product Details
PA5-92039
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELOVL4 (NP_0735631)
Conjugate
Form
Liquid
Concentration
1.13 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806361
Product Specific Information
Immunogen sequence: MGLLDSEPGS VLNVVSTALN DTVEFYRWTW SIADKRVENW PLMQSPWPTL SISTLYLLFV WLGPKWMKDR EPFQMRLVLI IYNFGMVLLN LFIFRELFMG; Positive Samples: U-87MG, HT-29, OVCAR3, A-431, HeLa; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
Target Information
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-keto acyl-CoA synthase ELOVL4; cancer/testis antigen 118; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4; Elongation of very long chain fatty acids protein 4; elongation of very long chain fatty acids-like 4; ELOVL FA elongase 4; ELOVL fatty acid elongase 4; FLJ17667; FLJ92876; Very long chain 3-ketoacyl-CoA synthase 4; Very long chain 3-oxoacyl-CoA synthase 4; Very long chain fatty acid elongase 4; very-long-chain 3-oxoacyl-CoA synthase 4
Gene Aliases: ADMD; CT118; ELOVL4; ISQMR; SCA34; STGD2; STGD3
UniProt ID: (Human) Q9GZR5, (Mouse) Q9EQC4
Entrez Gene ID: (Human) 6785, (Rat) 315851, (Mouse) 83603
biological_process
fatty acid elongation, saturated fatty acid
very long-chain fatty acid biosynthetic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
unsaturated fatty acid biosynthetic process
detection of visible light
sphingolipid biosynthetic process
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
long-chain fatty-acyl-CoA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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