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Positive test controls include: HepG2. The target is usually found in the following locations: Cytoplasm, cytoskeleton.
Immunogen sequence: GTFERGVGCL DFSKADSGVH LCVIDDSNEH MLTVWDWQKK AKGAEIKTTN EVVLAVEFHP TDANTIITCG KSHIFFWTWS GNSLTRKQGI FGKYEKPKFV QCLAFLGNGD VLTGDSGGVM LIWSKTTVEP TPGKGPKGVY QISKQIKAHD GSVFTLCQMR NGMLLTGGGK DRKIILWDHD LNPEREIEVP DQYGTIRAVA E
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT, interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Echinoderm microtubule-associated protein-like 4; EMAP-4; OTTHUMP00000201447; OTTHUMP00000201455; Restrictedly overexpressed proliferation-associated protein; Ropp 120
Gene Aliases: 4930443C24Rik; AI644019; C2orf2; ELP120; EMAP-4; EMAPL4; EML4; ROPP120
UniProt ID: (Human) Q9HC35, (Mouse) Q3UMY5
Entrez Gene ID: (Human) 27436, (Rat) 313861, (Mouse) 78798
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