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Product Details
BS-11551R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human EMX2, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Empty spiracles homolog 2; Empty spiracles-like protein 2; Homeobox protein EMX2
Gene Aliases: Emx-2; EMX2; Pdo; RGD1564797
UniProt ID: (Human) Q04743, (Mouse) Q04744
Entrez Gene ID: (Human) 2018, (Rat) 499380, (Mouse) 13797
regulation of transcription, DNA-templated
brain development
anterior/posterior pattern specification
regulation of gene expression
dentate gyrus development
cerebral cortex regionalization
cell proliferation in forebrain
forebrain cell migration
cerebral cortex development
neuron differentiation
forebrain development
response to drug
renal system development
multicellular organism development
Performance Guarantee
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