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Invitrogen
ENDOG Polyclonal Antibody
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ENDOG Antibody (PA5-103131) in IHC (P)
Immunohistochemistry analysis of ENDOG in mouse lung tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ENDOG polyclonal antibody (Product # PA5-103131) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103131
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ENDOG(Accession Q14249), corresponding to amino acid residues L36-D86.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852501
Product Specific Information
Antibody detects endogenous levels of total Endo G.
Target Information
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endo G; Endonuclease G, mitochondrial; mitochondrial endonuclease G
Gene Aliases: ENDOG
UniProt ID: (Human) Q14249, (Mouse) O08600
Entrez Gene ID: (Human) 2021, (Mouse) 13804, (Rat) 362100
in utero embryonic development
DNA metabolic process
DNA catabolic process
apoptotic DNA fragmentation
response to tumor necrosis factor
positive regulation of apoptotic process
response to antibiotic
nucleic acid phosphodiester bond hydrolysis
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of apoptotic DNA fragmentation
DNA recombination
aging
response to mechanical stimulus
response to estradiol
neuron death in response to oxidative stress
cellular response to calcium ion
cellular response to glucose stimulus
cellular response to hypoxia
cellular response to oxidative stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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