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Proteintech
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Immunogen sequence: IHKQEVLPP GLKYGIVLDA GSSRTTVYVY QWPAEKENNT GVVSQTFKCS VKGSGISSYG NNPQDVPRAF EECMQKVKGQ VPSHLHGSTP IHLGATAGMR LLRLQNETAA NEVLESIQSY FKSQPFDFRG AQIISGQEEG VYGWITANYL MGNFLEKNLW HMWVHPHGVE TTGALDLGGA STQISFVAGE KMDLNTSDIM QVSLYGYVYT LYTHSFQCYG RNEAEKKFLA MLLQNSPTKN HLTNPCYPRD YSISFTMGHV FDSLCTVDQR PESYNPNDVI TFEGTGDPSL CKEKVASIFD FKACHDQETC SFDGVYQPKI KGP (45-366 aa encoded by BC029869)
T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.
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Protein Aliases: CD39 antigen-like 3; CD39-like 3; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; ecto-ATPase 3; Ecto-ATPDase 3; Ectonucleoside triphosphate diphosphohydrolase 3; HB6; NTPDase 3
Gene Aliases: CD39L3; ENTPD3; HB6; NTPDase-3; NTPDase3
UniProt ID: (Human) O75355, (Mouse) Q8BFW6
Entrez Gene ID: (Human) 956, (Rat) 316077, (Mouse) 215446
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