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Product Details
PA5-82889
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ENY2. Recombinant protein control fragment (Product #RP-93770).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790045
Product Specific Information
Immunogen sequence: AINQKLMETG ERERLKELLR AKLIECGWKD QLKAHCKEVI KEKGLEHVTV DDLVAEITPK GRALVPDSVK KELLQRIRT
Target Information
ENY2 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: enhancer of yellow 2 homolog; Enhancer of yellow 2 transcription factor homolog; ENY 2; ENY-2; ENY2; Transcription and mRNA export factor ENY2
Gene Aliases: DC6; e(y)2; ENY2; Sus1
UniProt ID: (Human) Q9NPA8
Entrez Gene ID: (Human) 56943
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein transport
histone deubiquitination
poly(A)+ mRNA export from nucleus
positive regulation of transcription, DNA-templated
negative regulation of insulin secretion involved in cellular response to glucose stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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