Proteintech

EPB41 Polyclonal Antibody

FIGURE: 1 / 5

EPB41 Antibody (13014-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 13014-1-AP) EPB41 antibody at dilution of 1:8,000 incubated at room temperature for 1.5 hours.

EPB41 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13014-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

EPB41 Fusion Protein Ag4075 (1-299 aa encoded by BC039079)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.69 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MTTEKSLVT EAENSQHQQK EEGEEAINSG QQEPQQEESC QTAAEGDNWC EQKLKASNGD TPTHEDLTKN KERTSESRGL SRLFSSFLKR PKSQVSEEEG KEVESDKEKG EGGQKEIEFG TSLDEEIILK APIAAPEPEL KTDPSLDLHS LSSAETQPAQ EELREDPDFE IKEGEGLEEC SKIEVKEESP QSKAETELKA SQKPIRKHRN MHCKVSLLDD TVYECVVEKH AKGQDLLKRV CEHLNLLEED YFGLAIWDNA TSKTWLDSAK EIKKQVRGVP WNFTFNVKFY PPDPAQLTED (1-299 aa encoded by BC039079)

Target Information

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.

Frontiers of medicine

Yang Y,Li G,Wang Y,Sun Y,Xu C,Wei Z,Zhang S,Gao L,Liu S,Zhao J

Thu Dec 01 00:00:00 UTC 2022

Cell membrane skeletal protein 4.1R participates in entry of Zika virus into cells.

Virus research

Su S,Liu X,Tian RR,Qiao KX,Zheng CB,Gao WC,Yang LM,Kang QZ,Zheng YT

Wed Dec 01 00:00:00 UTC 2021

Cytoskeleton protein 4.1R regulates B-cell fate by modulating the canonical NF-κB pathway.

Immunology

Liang T,Guo Y,Li M,Ding C,Sang S,Zhou T,Shao Q,Liu X,Lu J,Ji Z,Wang T,Kang Q

Tue Dec 01 00:00:00 UTC 2020

Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.

Frontiers in oncology

Liu S,Liu J,Yu X,Shen T,Fu Q

Mon May 03 00:00:00 UTC 2021

7SL RNA in vertebrate red blood cells.

RNA (New York, N.Y.)

Talhouarne GJS,Gall JG

Sun Jul 01 00:00:00 UTC 2018

7SL RNA in vertebrate red blood cells.

RNA (New York, N.Y.)

Talhouarne GJS,Gall JG

Sun Jul 01 00:00:00 UTC 2018

7SL RNA in vertebrate red blood cells.

RNA (New York, N.Y.)

Talhouarne GJS,Gall JG

Sun Jul 01 00:00:00 UTC 2018

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.

The EMBO journal

Kotak S,Busso C,Gönczy P

Mon Aug 18 00:00:00 UTC 2014

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.

The EMBO journal

Kotak S,Busso C,Gönczy P

Mon Aug 18 00:00:00 UTC 2014

Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.

Cell

Kiyomitsu T,Cheeseman IM

Thu Jul 18 00:00:00 UTC 2013

Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.

Cell

Kiyomitsu T,Cheeseman IM

Thu Jul 18 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: 4.1R; Band 4.1; elliptocytosis 1, RH-linked; EPB4.1; Erythrocyte membrane protein band 4.1; erythrocyte protein band 4.1; erythrocyte surface protein band 4.1; P4.1; Protein 4.1; Protein 4.1R

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Gene Aliases: 4.1R; AI415518; D4Ertd442e; E41P; EL1; Elp-1; Elp1; Epb4.1; EPB41; HE; Kiaa4056; mKIAA4056; RGD1564762

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UniProt ID: (Human) P11171, (Mouse) P48193

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Entrez Gene ID: (Human) 2035, (Mouse) 269587, (Rat) 313052

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Function(s)

actin binding structural constituent of cytoskeleton protein binding calmodulin binding 1-phosphatidylinositol binding spectrin binding structural molecule activity cytoskeletal protein binding

Process(es)

regulation of cell shape actin cytoskeleton organization cortical actin cytoskeleton organization positive regulation of protein binding blood circulation biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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EPB41 Polyclonal Antibody

EPB41 Antibody (13014-1-AP) in WB

Product Details

13014-1-AP

Western Blot (WB)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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