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Invitrogen
EPB41L3 Polyclonal Antibody
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Product Details
PA1-46313
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to internal residues 400-500 of the human protein. [Swiss-Prot# Q9Y2J2]
Conjugate
Form
Liquid
Concentration
1.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 30% glycerol
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2098485
Product Specific Information
This EPB41L3 antibody is useful for Western blot, where bands are seen at ~120 and 96 kDa.
It detects both isoforms A and B in mouse brain lysates.
It detects human isoform A strongly and isoform B more weakly.Suggested positive control: human and mouse brain lysate, HeLa whole cell lysate, Hela whole cell lysate, mouse brain lysate, human brain lysate.
Target Information
Critical growth regulator in the pathogenesis of meningiomas. Its human homolog acts as a tumor suppressor and binds 14-3-3 proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 130kDa Protein 4.1B MEF cell isoform; 4.1B; 60kDa 4.1B MEF cell isoform; Band 4.1-like protein 3; DAL-1; Differentially expressed in adenocarcinoma of the lung protein 1; Erythrocyte membrane protein band 4.1-like 3; erythrocyte protein band 4.1-like 3; FLJ37633; HGNC:3380; mDAL-1
Gene Aliases: 4.1B; DAL-1; DAL1; DAL1P; Epb4.1l3; EPB41L3; KIAA0987; NBL3; XELAEV_18031863mg
UniProt ID: (Human) Q9Y2J2, (Mouse) Q9WV92
Entrez Gene ID: (Human) 23136, (Mouse) 13823, (Rat) 116724, (Xenopus) 398970
regulation of cell growth
protein localization to paranode region of axon
apoptotic process
cytoskeletal anchoring at plasma membrane
biological_process
regulation of cell shape
cortical cytoskeleton organization
cortical actin cytoskeleton organization
paranodal junction assembly
myelin maintenance
neuron projection morphogenesis
protein localization to juxtaparanode region of axon
protein localization to plasma membrane
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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