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The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
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Protein Aliases: ependymin 2; ependymin related protein 1; ependymin related protein 2; mammalian ependymin related protein 1; Mammalian ependymin-related protein 1; MERP-1; upregulated in colorectal cancer gene 1; Upregulated in colorectal cancer gene 1 protein
Gene Aliases: AU040950; AV006210; Epdm2; EPDR; EPDR1; Epdr2; MERP-1; MERP-2; MERP1; MERP2; UCC1
UniProt ID: (Human) Q9UM22, (Mouse) Q99M71, (Rat) Q5XII0
Entrez Gene ID: (Human) 54749, (Mouse) 105298, (Rat) 291180
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