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Proteintech
EPHA7 Monoclonal Antibody (1A7E5)
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FIGURE: 1 / 6
EPHA7 Antibody (66667-1-IG) in WB
Untreated and PNGase F-treated lysates of rat brain tissue were subjected to SDS PAGE followed by western blot with 66667-1-Ig (EPHA7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. PNGase F was obtained from Atagenix (cat.NO. ata808).
Product Details
66667-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A7E5
Immunogen
EPHA7 Fusion Protein Ag3813 (29-279 aa encoded by BC027940)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AAKEVLLLD SKAQQTELEW ISSPPNGWEE ISGLDENYTP IRTYQVCQVM EPNQNNWLRT NWISKGNAQR IFVELKFTLR DCNSLPGVLG TCKETFNLYY YETDYDTGRN VRENLYVKID TIAADESFTQ GDLGERKMKL NTEVREIGPL SKKGFYLAFQ DVGACIALVS VKVYYKKCWS IIENLAIFPD TVTGSEFSSL VEVRGTCVSS AEEEAENAPR MHCSAEGEWL VPIGKCICKA GYQQKGDTCE CK (29-279 aa encoded by BC027940)
Target Information
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Developmental kinase 1; EBK; EHK-3; EK11; Embryonic brain kinase; epa7; EPH homology kinase 3; Eph homology kinase-3; EPH-like kinase 11; EPHA7-S; ephrin receptor EphA7; Ephrin type-A receptor 7; mDK-1; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3
Gene Aliases: Cek11; Ebk; EHK-3; EHK3; EK11; EPHA7; HEK11; Mdk1
UniProt ID: (Human) Q15375, (Rat) P54759, (Mouse) Q61772
Entrez Gene ID: (Human) 2045, (Rat) 171287, (Mouse) 13841
protein tyrosine kinase activity
GPI-linked ephrin receptor activity
protein binding
ATP binding
axon guidance receptor activity
chemorepellent activity
ephrin receptor binding
ephrin receptor activity
nucleotide binding
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
signal transduction
brain development
phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
regulation of protein autophosphorylation
positive regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
branching morphogenesis of a nerve
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
regulation of ERK1 and ERK2 cascade
nephric duct morphogenesis
protein phosphorylation
apoptotic process
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
positive regulation of protein phosphorylation
negative regulation of collateral sprouting
negative regulation of synapse assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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