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Invitrogen
EPM2A Polyclonal Antibody
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FIGURE: 1 / 4
EPM2A Antibody (PA5-28073) in ICC/IF
EPM2A Polyclonal Antibody detects EPM2A protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: EPM2A protein stained by EPM2A Polyclonal Antibody (Product # PA5-28073) diluted at 1:500. Blue: Hoechst 33343 staining.
Product Details
PA5-28073
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Laforin. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 40% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545549
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epilepsy, progressive myoclonus type 2, Lafora disease (laforin); EPM2A; Glucan phosphatase; Glycogen phosphatase; Lafora PTPase; Laforin; LAFPTPase; RP1-28C20.2
Gene Aliases: EPM2; EPM2A; MELF
UniProt ID: (Human) O95278
Entrez Gene ID: (Human) 7957
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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