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Proteintech
EPS8 Polyclonal Antibody
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Product Details
12455-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPS8 Fusion Protein Ag3121 (13-267 aa encoded by BC030010)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GMYPSQMNG YGSSPTFSQT DREHGSKTSA KALYEQRKNY ARDSVSSVSD ISQYRVEHLT TFVLDRKDAM ITVDDGIRKL KLLDAKGKVW TQDMILQVDD RAVSLIDLES KNELENFPLN TIQHCQAVMH SCSYDSVLAL VCKEPTQNKP DLHLFQCDEV KANLISEDIE SAISDSKGGK QKRRPDALRM ISNADPSIPP PPRAPAPAPP GTVTQVDVRS RVAAWSAWAA DQGDFEKPRQ YHEQEETPEM MAARID (13-267 aa encoded by BC030010)
Target Information
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Epidermal growth factor receptor kinase substrate 8
Gene Aliases: DFNB102; EPS8
UniProt ID: (Human) Q12929
Entrez Gene ID: (Human) 2059
signal transduction
epidermal growth factor receptor signaling pathway
cell proliferation
adult locomotory behavior
regulation of cell shape
positive regulation of signal transduction
exit from mitosis
Rac protein signal transduction
regulation of actin filament length
actin cytoskeleton reorganization
dendritic cell migration
behavioral response to ethanol
barbed-end actin filament capping
actin filament bundle assembly
actin crosslink formation
actin polymerization-dependent cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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