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Invitrogen
ERC1 Polyclonal Antibody
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FIGURE: 1 / 1
ERC1 Antibody (PA5-97221) in WB
Western blot analysis of ERC1 in extracts of various cell lines. Samples were incubated with ERC1 Polyclonal antibody (Product # PA5-97221) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
Product Details
PA5-97221
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 700-850 of human ERC1 (NP_8298841)
Conjugate
Form
Liquid
Concentration
1.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809023
Product Specific Information
Immunogen sequence: EIALEQKKEE CLKMESQLKK AHEAALEARA SPEMSDRIQH LEREITRYKD ESSKAQAEVD RLLEILKEVE NEKNDKDKKI AELERQVKDQ NKKVANLKHK EQVEKKKSAQ MLEEARRRED NLNDSSQQLQ DSLRKKDDRI EELEEALRES V; Positive Samples: HepG2, Jurkat, NIH/3T3, Rat brain; Cellular Location: Cytoplasm, Golgi apparatus membrane, Membrane, Peripheral membrane protein
Target Information
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAST2; CAZ-associated structural protein 2; ELKS/Rab6-interacting/CAST family member 1; ERC protein 1; ERC-1; FLJ31750; MGC12974; OTTHUMP00000160633; RAB6 interacting protein 2; RAB6-interacting protein 2; RIM-Binding Protein
Gene Aliases: 4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST; CAST2; ELKS; ERC; ERC-1; ERC1; ERC1b; KIAA1081; mKIAA1081; RAB6IP2; RAB6IP2A; RAB6IP2B
UniProt ID: (Human) Q8IUD2, (Mouse) Q99MI1
Entrez Gene ID: (Human) 23085, (Rat) 266806, (Mouse) 111173
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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