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NeoBiotechnologies
ERG Recombinant Rabbit Monoclonal Antibody (ERG, 22R)
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ERG Antibody (2078-RBM2-P1) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human brain using ERG Recombinant Monoclonal Antibody (Product # 2078-RBM2-P1) at 1 µg/mL for 30 min at RT. HIER: Tris/EDTA pH 9; 95°C/45 min. SecondaryAb: HRP-Polymer:30 mins; DAB:5 min.
Product Details
2078-RBM2-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ERG, 22R
Immunogen
Synthetic peptide corresponding to residues within aa450 to C-terminus of ERG was used as an immunogen.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Target Information
v-ets erythroblastosis virus E26 oncogene like isoform 2 (ERG) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERG/EWS fusion gene; ERG/FUS fusion gene; ERG/TMPSSR2 fusion gene; ERG1; erythroblast transformation-specific transcription factor ERG variant 10; ets-related; H Kv11.3; HGNC:3446; KCNH2; Oncogene ERG; OTTHUMP00000115970; OTTHUMP00000208036; TMPRSS2/ERG fusion; Transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); Transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
Gene Aliases: ERG; erg-3; p55
UniProt ID: (Human) P11308
Entrez Gene ID: (Human) 2078
endocardial cushion development
endocardial cushion to mesenchymal transition involved in heart valve formation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
multicellular organism development
cell proliferation
cell migration
cell differentiation
positive regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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