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OriGene
ERLIN1 Monoclonal Antibody (OTI4B1), TrueMAB™
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ERLIN1 Antibody (TA809148) in IHC (P)
Immunohistochemical staining of paraffin-embedded human lymph node tissue within the normal limits using anti-ERLIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809148)(1:2000).
Product Details
TA809148
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI4B1
Immunogen
Human recombinant protein fragment corresponding to amino acids 107-346 of human ERLIN1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; Endoplasmic reticulum lipid raft-associated protein 1; Erlin-1; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; SPFH domain family, member 1; SPFH domain-containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Gene Aliases: C10orf69; Erlin-1; ERLIN1; KE04; KEO4; SPFH1; SPG62
UniProt ID: (Human) O75477
Entrez Gene ID: (Human) 10613
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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