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Immunogen sequence: LHSKHDEEQK VWDEEIDDDD DDNCNNDEDE VRVIEFKKKH EEVSQFKEEG DASEDSPLSS ASSQAVTPDE QPTLGKKSDI SRNAYSRYNT ISYRK
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 69%.
ERMIN plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. ERMIN may play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ermin; ermin, ERM-like protein; JN; Juxtanodin
Gene Aliases: ERMN; JN; KIAA1189
UniProt ID: (Human) Q8TAM6
Entrez Gene ID: (Human) 57471
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