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Bioss
ERRFI1 Polyclonal Antibody
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ERRFI1 Antibody (BS-14630R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse testis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with ERRFI1 Polyclonal Antibody, Unconjugated (bs-14630R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-14630R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ERRFI1, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERBB receptor feedback inhibitor 1; Gene 33 polypeptide; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; RALT; Receptor-associated late transducer
Gene Aliases: 1300002F13Rik; RALT; 33; AI788755; ERRFI1; gene 33; GENE-33; MIG-6; MIG6; Ralt; RGD1307599; Xxx
UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7, (Rat) P05432
Entrez Gene ID: (Human) 54206, (Mouse) 74155, (Rat) 313729
negative regulation of epidermal growth factor-activated receptor activity
stress-activated protein kinase signaling cascade
negative regulation of protein autophosphorylation
negative regulation of interleukin-1 beta production
negative regulation of collagen biosynthetic process
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tumor necrosis factor biosynthetic process
skin morphogenesis
regulation of keratinocyte differentiation
lung alveolus development
negative regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung epithelium development
regulation of type B pancreatic cell proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of cardiac muscle hypertrophy in response to stress
response to stress
cellular response to insulin stimulus
cellular response to platelet-derived growth factor stimulus
positive regulation of GTPase activity
cellular response to epidermal growth factor stimulus
cellular hyperosmotic response
cellular response to dexamethasone stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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