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Bethyl Laboratories
ERp5 Polyclonal Antibody
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ERp5 Antibody (A304-519A) in IHC (P)
Detection of human ERp5 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-ERp5 (Product # A304-519A) (Lot 1) used at a dilution of 1:5,000 (0.2 µg/mL). Detection: DAB. Counterstain: IHC Hematoxylin (blue).
Product Details
A304-519A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 250 to 300 of human Endoplasmic Reticulum Protein 5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Golden hamster and Orangutan
Target Information
P5 is a novel protein that was originally identified in humans. Functionally, P5 has been shown to have peptide binding ability and chaperone activity specific to certain proteins. P5 shares several structural similarities to PDI, an important protein of the ER. The deduced amino acid sequence of P5 shows that it contains the ER retention signal KDEL. P5 also contains two CXXC-like motifs, a motif responsible for oxidoreductase activity. These two CXXC motifs are found on the N- and C-terminus of the protein, one at each end. Studies suggest that the N-terminal CXXC motif is more important than the second for isomerase activity. Contrary to most of the PDI-like proteins, P5 is not stress-inducible.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum protein 5; ER protein 5; protein disulfide isomerase family A, member 6; Protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; Protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain-containing protein 7
Gene Aliases: 1700015E05Rik; AL023058; C77895; CaBP5; ERP5; P5; PDIA6; TXNDC7
UniProt ID: (Human) Q15084, (Mouse) Q922R8
Entrez Gene ID: (Human) 10130, (Mouse) 71853
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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