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Proteintech
ERp72 Monoclonal Antibody (1D5F3)
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Product Details
66365-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D5F3
Immunogen
ERp72 Fusion Protein Ag6873 (294-645 aa encoded by BC000425)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KQVQEFLKD GDDVIIIGVF KGESDPAYQQ YQDAANNLRE DYKFHHTFST EIAKFLKVSQ GQLVVMQPEK FQSKYEPRSH MMDVQGSTQD SAIKDFVLKY ALPLVGHRKV SNDAKRYTRR PLVVVYYSVD FSFDYRAATQ FWRSKVLEVA KDFPEYTFAI ADEEDYAGEV KDLGLSESGE DVNAAILDES GKKFAMEPEE FDSDTLREFV TAFKKGKLKP VIKSQPVPKN NKGPVKVVVG KTFDSIVMDP KKDVLIEFYA PWCGHCKQLE PVYNSLAKKY KGQKGLVIAK MDATANDVPS DRYKVEGFPT IYFAPSGDKK NPVKFEGGDR DLEHLSKFIE EHATKLSRTK EEL (294-645 aa encoded by BC000425)
Target Information
ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EC 5.3.4.1; Endoplasmic reticulum resident protein 70; Endoplasmic reticulum resident protein 72; ER protein 70; ER protein 72; protein disu; protein disulfide isomerase family A, member 4; protein disulfide isomerase related protein (calcium-binding protein, intestinal-related); protein disulfide isomerase-associated 4; Protein disulfide-isomerase A4; Protein ERp-72; testicular tissue protein Li 137
Gene Aliases: ERp-72; ERP70; ERP72; PDIA4
UniProt ID: (Human) P13667
Entrez Gene ID: (Human) 9601
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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