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Product Details
21045-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ESRP1 Fusion Protein Ag15386 (27-226 aa encoded by BC099916)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EKELILLFW KVVDLANKKV GQLHEVLVRP DQLELTEDCK EETKIDVESL SSASQLDQAL RQFNQSVSNE LNIGVGTSFC LCTDGQLHVR QILHPEASKK NVLLPECFYS FFDLRKEFKK CCPGSPDIDK LDVATMTEYL NFEKSSSVSR YGASQVEDMG NIILAMISEP YNHRFSDPER VNYKFESGTC SKMELIDDNT V (27-226 aa encoded by BC099916)
Target Information
RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Epithelial splicing regulatory protein 1; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A
Gene Aliases: 2210008M09Rik; A630065D16; BC031468; ESRP1; RBM35A; RMB35A
UniProt ID: (Human) Q6NXG1, (Mouse) Q3US41
Entrez Gene ID: (Human) 54845, (Mouse) 207920
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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