Invitrogen

ETV1 Polyclonal Antibody

6 Published Figures

6 References

View all (11) ETV1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (3)
Published Figures (6)

ETV1 Antibody in Immunohistochemistry (IHC)

FIGURE: 1 / 9

ETV1 Antibody (PA5-41484) in IHC

Immunohistochemistry analysis of brain, cortex tissue using an anti-ETV1 polyclonal antibody (Product # PA5-41484).

ETV1 Antibody in Western Blot, Immunohistochemistry (WB, IHC)

Product Image Gallery

Product Details

PA5-41484

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

5 µg/mL

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human ETV1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2608631

Product Specific Information

Peptide sequence: PDNQRPLLKT DMERHINEED TVPLSHFDES MAYMPEGGCC NPHPYNEGYV

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 86%

Target Information

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.

Annals of translational medicine

Askar P,Xu J,Hu J,Shangguan J,Sun H,Zhou S,Yang X,Chen G,Su W,Gu Y

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Immunohistochemistry

Mon Aug 01 00:00:00 UTC 2022

The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination.

Annals of translational medicine

Askar P,Xu J,Hu J,Shangguan J,Sun H,Zhou S,Yang X,Chen G,Su W,Gu Y

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Immunohistochemistry

Mon Aug 01 00:00:00 UTC 2022

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer.

eLife

Inoue Y,Nikolic A,Farnsworth D,Shi R,Johnson FD,Liu A,Ladanyi M,Somwar R,Gallo M,Lockwood WW

Published figure using ETV1 polyclonal antibody (Product # PA5-41484) in Western Blot

Mon Jun 14 00:00:00 UTC 2021

Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors.

Scientific reports

Kocsmár É,Kocsmár I,Szalai L,Lendvai G,Szijártó A,Schaff Z,Kiss A,Kovalszky I,Papp G,Lotz G

PA5-41484 was used in Immunohistochemistry to characterize nine MGs and GACs present in the same surgical specimen by cross-testing the markers of the major pathogenetic pathways of both tumor types.

Thu Dec 17 00:00:00 UTC 2020

Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors.

Scientific reports

Kocsmár É,Kocsmár I,Szalai L,Lendvai G,Szijártó A,Schaff Z,Kiss A,Kovalszky I,Papp G,Lotz G

PA5-41484 was used in Immunohistochemistry to characterize nine MGs and GACs present in the same surgical specimen by cross-testing the markers of the major pathogenetic pathways of both tumor types.

Thu Dec 17 00:00:00 UTC 2020

The role of miR-24 as a race related genetic factor in prostate cancer.

Oncotarget

Hashimoto Y,Shiina M,Kato T,Yamamura S,Tanaka Y,Majid S,Saini S,Shahryari V,Kulkarni P,Dasgupta P,Mitsui Y,Sumida M,Deng G,Tabatabai L,Kumar D,Dahiya R

PA541484 was used in western blot to suggest that miR-24 is a central regulator of race-related prostate cancer

Tue Mar 07 00:00:00 UTC 2017

Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians.

Oncotarget

Shiina M,Hashimoto Y,Kato T,Yamamura S,Tanaka Y,Majid S,Saini S,Varahram S,Kulkarni P,Dasgupta P,Mitsui Y,Sumida M,Tabatabai L,Deng G,Kumar D,Dahiya R

PA541484 was used in western blot to demonstrate that differential expression of miR-34b and AR are associated with prostate cancer aggressiveness in African-Americans

Tue Jan 31 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: DKFZp781L0674; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; MGC104699; MGC120533; MGC120534

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Gene Aliases: ER81; ETV1

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UniProt ID: (Human) P50549

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Entrez Gene ID: (Human) 2115

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding

Process(es)

transcription from RNA polymerase II promoter axon guidance muscle organ development mechanosensory behavior positive regulation of transcription from RNA polymerase II promoter peripheral nervous system neuron development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ETV1 Polyclonal Antibody

ETV1 Antibody (PA5-41484) in IHC

Product Details

PA5-41484

Western Blot (WB)

Immunohistochemistry (IHC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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