Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ETV1 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-89150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 80-300 of human ETV1 (NP_0049472)
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805388
Product Specific Information
Immunogen sequence: AFHGLPLKIK KEPHSPCSEI SSACSQEQPF KFSYGEKCLY NVSAYDQKPQ VGMRPSNPPT PSSTPVSPLH HASPNSTHTP KPDRAFPAHL PPSQSIPDSS YPMDHRFRRQ LSEPCNSFPP LPTMPREGRP MYQRQMSEPN IPFPPQGFKQ EYHDPVYEHN TMVGSAASQS FPPPLMIKQE PRDFAYDSEV PSCHSIYMRQ EGFLAHPSRT EGCMFEKGPR Q
Target Information
ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DKFZp781L0674; ets related protein 81; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; MGC104699; MGC120533; MGC120534
Gene Aliases: ER81; Etsrp81; ETV1
UniProt ID: (Human) P50549, (Mouse) P41164
Entrez Gene ID: (Human) 2115, (Rat) 362733, (Mouse) 14009
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
sequence-specific DNA binding
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
axon guidance
muscle organ development
mechanosensory behavior
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support