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Bethyl Laboratories
ETV3 Polyclonal Antibody
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ETV3 Antibody (A303-737A) in WB
Detection of human ETV3 by western blot and immunoprecipitation. Samples: Whole cell lysate from Jurkat (15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded), HeLa (H; 50 µg) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-ETV3 antibody (Product # A303-737A) used for WB at 0.1 µg/mL (A) and 1 µg/mL (B) and used for IP at 6 µg/mg lysate. ETV3 was also immunoprecipitated by rabbit anti-ETV3 antibody A303-736A, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30... View More
Product Details
A303-737A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 450 and 500 of human Ets Variant 3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
Target Information
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ETS domain transcriptional repressor PE1; ETS translocation variant 3; ets variant gene 3, ETS family transcriptional repressor; Mitogenic Ets transcriptional suppressor; PE-1
Gene Aliases: bA110J1.4; ETV3; METS; PE-1; PE1
UniProt ID: (Human) P41162
Entrez Gene ID: (Human) 2117
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
molecular_function
DEAD/H-box RNA helicase binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
biological_process
negative regulation of cell proliferation
cell differentiation
cellular response to granulocyte macrophage colony-stimulating factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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