Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
ETV5 Monoclonal Antibody (2A4A4)
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
66657-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2A4A4
Immunogen
ETV5 Fusion Protein Ag3708 (160-510 aa encoded by BC007333)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SGHAPAAGP VQGVGPAPAP HSLPEPGPQQ QTFAVPRPPH QPLQMPKMMP ENQYPSEQRF QRQLSEPCHP FPPQPGVPGD NRPSYHRQMS EPIVPAAPPP PQGFKQEYHD PLYEHGVPGM PGPPAHGFQS PMGIKQEPRD YCVDSEVPNC QSSYMRGGYF SSSHEGFSYE KDPRLYFDDT CVVPERLEGK VKQEPTMYRE GPPYQRRGSL QLWQFLVTLL DDPANAHFIA WTGRGMEFKL IEPEEVARRW GIQKNRPAMN YDKLSRSLRY YYEKGIMQKV AGERYVYKFV CDPDALFSMA FPDNQRPFLK AESECHLSEE DTLPLTHFED SPAYLLDMDR CSSLPYAEGF AY (160-510 aa encoded by BC007333)
Target Information
ETS variant 5, transcription factor of the ETS family, divergent member of the winged helix-turn-helix superfamily, expressed in brain, placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ETS translocation variant 5; ets-related molecule; Ets-related protein ERM
Gene Aliases: ERM; ETV5
UniProt ID: (Human) P41161
Entrez Gene ID: (Human) 2119
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
transcription from RNA polymerase II promoter
neuromuscular synaptic transmission
locomotory behavior
cell differentiation
cellular response to oxidative stress
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
male germ-line stem cell asymmetric division
regulation of synapse organization
positive regulation of glial cell proliferation
regulation of branching involved in mammary gland duct morphogenesis
skeletal muscle acetylcholine-gated channel clustering
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support