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Invitrogen
EVER2 Polyclonal Antibody
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Product Details
PA5-20526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide from near the center of human EVER2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153881
Product Specific Information
A suggested positive control is Jurkat cell lysate.
PA5-20526 can be used with blocking peptide PEP-0646.
Target Information
Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epidermodysplasia verruciformis 2; Epidermodysplasia verruciformis protein 2; Epidermodysplasia verruciformis protein 2 homolog; transmembrane channel-like 8; Transmembrane channel-like protein 8
Gene Aliases: EV2; EVER2; EVIN2; mFLJ00400; TMC8
UniProt ID: (Human) Q8IU68, (Mouse) Q7TN58
Entrez Gene ID: (Human) 147138, (Mouse) 217356, (Rat) 688276
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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