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Product Details
H00011336-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EXOC3 (NP_009208.2, 1 a.a. approximately 745 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKETDREAVA TAVQRVAGML QRPDQLDKVE QYRRREARKK ASVEARLKAA IQSQLDGVRT GLSQLHNALN DVKDIQQSLA DVSKDWRQSI NTIESLKDVK DAVVQHSQLA AAVENLKNIF SVPEIVRETQ DLIEQGALLQ AHRKLMDLEC SRDGLMYEQY RMDSGNTRDM TLIHGYFGST QGLSDELAKQ LWMVLQRSLV TVRRDPTLLV SVVRIIEREE KIDRRILDRK KQTGFVPPGR PKNWKEKMFT ILERTVTTRI EGTQADTRES DKMWLVRHLE IIRKYVLDDL IVAKNLMVQC FPPHYEIFKN LLNMYHQALS TRMQDLASED LEANEIVSLL TWVLNTYTST EMMRNVELAP EVDVGTLEPL LSPHVVSELL DTYMSTLTSN IIAWLRKALE TDKKDWVKET EPEADQDGYY QTTLPAIVFQ MFEQNLQVAA QISEDLKTKV LVLCLQQMNS FLSRYKDEAQ LYKEEHLRNR QHPHCYVQYM IAIINNCQTF KESIVSLKRK YLKNEVEEGV SPSQPSMDGI LDAIAKEGCS GLLEEVFLDL EQHLNELMTK KWLLGSNAVD IICVTVEDYF NDFAKIKKPY KKRMTAEAHR RVVVEYLRAV MQKRISFRSP EERKEGAEKM VREAEQLRFL FRKLASGFGE DVDGYCDTIV AVAEVIKLTD PSLLYLEVST LVSKYPDIRD DHIGALLAVR GDASRDMKQT IMETLEQGPA QASPSYVPLF KDIVVPSLNV AKLLK
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exocyst complex component 3; Exocyst complex component Sec6; Sec 6 homolog; SEC6-like 1
Gene Aliases: EXOC3; SEC6; SEC6L1; Sec6p
UniProt ID: (Human) O60645
Entrez Gene ID: (Human) 11336
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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