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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Endocan Antibodies

          Invitrogen

          Endocan Polyclonal Antibody

          1 Published Figure
          3 References
          View all (10) Endocan antibodies

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          Datasheet
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          Datasheet
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          Cite Endocan Polyclonal Antibody

          • Antibody Testing Data (2)
          • Published Figures (1)
          Endocan Antibody in Immunohistochemistry (Frozen) (IHC (F))
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          Endocan Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Endocan Antibody (PA5-47237) in IHC (F)

          Immunohistochemical analysis of Endocan in perfusion fixed frozen sections of mouse embryo (13 d.p.c.). Samples were incubated with Endocan polyclonal antibody (Product # PA5-47237) using a dilution of 5 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to the retina. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Endocan Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Endocan Antibody in Neutralization (Neu)
          Endocan Antibody in Western Blot, Immunocytochemistry, Immunohistochemistry (WB, ICC/IF, IHC)

          Product Details

          PA5-47237

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Frozen) (IHC (F))

          5-15 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication

          Neutralization (Neu)

          1-5 µg/mL
          -
          Product Specifications

          Species Reactivity

          Mouse

          Published species

          Mouse

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Mouse myeloma cell line NS0-derived recombinant mouse Endocan/ESM-1 Trp20-Arg184
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 5% trehalose

          Contains

          No Preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2576804

          Product Specific Information

          In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human Endocan is observed.

          Reconstitute at 0.2 mg/mL in sterile PBS.

          Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

          Target Information

          Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Endothelial cell-specific molecule 1; ESM-1; IGFBP-rp6

          View more View less

          Gene Aliases: 0610042H23Rik; AV004503; ESM-1; Esm1

          View more View less

          UniProt ID: (Mouse) Q9QYY7

          View more View less

          Entrez Gene ID: (Mouse) 71690

          View more View less

          Function(s)
          hepatocyte growth factor receptor binding integrin binding insulin-like growth factor binding
          Process(es)
          angiogenesis regulation of cell growth sprouting angiogenesis positive regulation of cell proliferation positive regulation of hepatocyte growth factor receptor signaling pathway
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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