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Invitrogen
Endothelin B Receptor Polyclonal Antibody
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Product Details
PA5-33498
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EDNRB.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550878
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Dog (100%) Gorilla, Gibbon (95%) Monkey (89%) Marmoset (84%).
Target Information
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AU022549; endothelin receptor B; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; endothelin-B receptor; ET-B; Et-b receptor; Et-b-r; ET-RB; Etb receptor; Etb-svr; RP11-318G21.1
Gene Aliases: ABCDS; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A
UniProt ID: (Dog) P56497, (Human) P24530
Entrez Gene ID: (Dog) 403862, (Human) 1910
regulation of blood pressure
vasoconstriction
enteric nervous system development
endothelin receptor signaling pathway
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
positive regulation of protein phosphorylation
regulation of pH
cell surface receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
nervous system development
peripheral nervous system development
posterior midgut development
aging
positive regulation of cell proliferation
negative regulation of neuron maturation
response to organic cyclic compound
vein smooth muscle contraction
sensory perception of pain
cGMP-mediated signaling
melanocyte differentiation
regulation of fever generation
negative regulation of cellular protein metabolic process
enteric smooth muscle cell differentiation
positive regulation of urine volume
positive regulation of renal sodium excretion
epithelial fluid transport
vasodilation
negative regulation of apoptotic process
macrophage chemotaxis
response to pain
regulation of epithelial cell proliferation
regulation of sensory perception of pain
positive regulation of penile erection
cellular response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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