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The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115)); E-MAP-115; Ensconsin; Epithelial microtubule-associated protein of 115 kDa; MAP-7; Microtubule-associated protein 7
Gene Aliases: E-MAP-115; EMAP115; MAP-7; MAP7; mshi; mste; Mtap7; R75000; ste
UniProt ID: (Human) Q14244, (Mouse) O88735
Entrez Gene ID: (Human) 9053, (Mouse) 17761, (Rat) 293016
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