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Invitrogen
Erythrocytes Monoclonal Antibody (SFL23.6)
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Product Details
MA1-35369
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
SFL23.6
Immunogen
Fetal hepatocytes
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
purified
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1074262
Product Specific Information
SFL23.6 is directed against an erythroid cell surface antigen, which is not glycophorin A. It shows a well-defined reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. SFL23.6 is positive on erythroleukemias and can be used to distinguish bone marrow nucleated erythroid precursors from malignant cells in bone marrow specimens
Target Information
Erythrocytes, commonly known as red blood cells, are the primary cellular component responsible for oxygen transport within the blood. Originating from hematopoietic stem cells in the bone marrow, these cells undergo a maturation process called erythropoiesis, which necessitates key nutrients such as iron, vitamin B12, and folate. Structurally, erythrocytes have a biconcave disc shape, enhancing their surface area for gas exchange. Beyond their oxygen-carrying role, erythrocytes possess immune functions, including antigen presentation and pathogen binding, contributing to the innate immune system. Their membrane surface proteins and intracellular substances play pivotal roles in immuno-regulation, varying significantly among different disease states.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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