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MA1-40268 detects Ethenoadenosine.
MA1-40268 has been successfully used in ELISA, flow cytometry, immunohistochemistry (frozen), immunoprecipitation, Western blot applications.
The MA1-40268 immunogen is human ethenoadenosine.
The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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