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Immunogen sequence: MIPPQEASA RRREIEDKLK QEEETLSFIR DSLEKSDQLT KNMVSILSSF ESRLMKLENS IIPVHKQTEN LQRLQENVEK TLSCLDHVIS YYHVASDTEK IIREGPTGRL EEYLGSMAKI QKAVEYFQDN SPDSPELNKV KLLFERGKEA LESEFRSLMT RHSKVVSPVL ILDLISGDDD LEAQEDVTLE HLPESVLQDV IRISRWLVEY GRNQDFMNVY YQIRSSQLDR SIKGLKEHFH KSSSSSGVPY SPAIPNKRKD TPTKKPVKRP GTIRKAQNLL KQYSQHGLDG KKGGSNLIPL EGRDDMLDVE TDAYIHCVSA FVKLAQSEYQ LLADIIPEHH QKKTFDSLIQ DALDG (1-354 aa encoded by BC011045)
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exocyst complex component 7; Exocyst complex component Exo70; exocyst component protein 70 kDa homolog; HGNC:23214; rExo70
Gene Aliases: 2-5-3p; EX070; EXO70; Exo70p; EXOC1; EXOC7; KIAA1067; sec70; YJL085W
UniProt ID: (Human) Q9UPT5, (Mouse) O35250, (Rat) O54922
Entrez Gene ID: (Human) 23265, (Mouse) 53413, (Rat) 64632
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