Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
F1A alpha Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-59906
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human F1A alpha. Recombinant protein control fragment (Product #RP-98129).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2641187
Product Specific Information
Immunogen sequence: RFAQVFSQMI HLNETVKAPD IECVLRCSVL EIEQSMNRVK NISDADVHNA MDNYECNLYT FLYLVCISTK TQCSEEDQCK INKQIYNLIH
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b. F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DKFZp451E0710; F1A-alpha; FEM-1-like death receptor binding protein; Fem-1-like death receptor-binding protein alpha; Fem-1-like in apoptotic pathway protein alpha; FEM1-beta; FEM1b; FIAA; Protein fem-1 homolog B
Gene Aliases: F1A-ALPHA; F1AA; FEM1-beta; FEM1B; KIAA0396
UniProt ID: (Human) Q9UK73
Entrez Gene ID: (Human) 10116
apoptotic process
protein ubiquitination
regulation of ubiquitin-protein transferase activity
branching involved in prostate gland morphogenesis
epithelial cell maturation involved in prostate gland development
regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of DNA damage checkpoint
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support