Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • F4/80 Antibodies

          Invitrogen

          F4/80 Monoclonal Antibody (BM8)

          Advanced Verification
          60 Published Figures
          116 References
          View all (61) F4/80 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite F4/80 Monoclonal Antibody (BM8)

          • Published Figures (60)
          • Advanced Verification (1)
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 61

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          F4/80 Antibody (MF48000) in IHC (P)

          Cell reports 2021 - Figure 5. The composition of tumor-associated macrophages varies with treatment modality (A) Immunohistochemical staining with F4/80 shows a dramatic increase in macrophages with radiation therapy. Student's t test. n = 3 animals per treatment group. Rsssssesults are expressed as mean +- SEM. **p < 0.01. Field: 3,190 x 1,974 mum. Scale bar: 200 muM. (B) UMAP plots of myeloid cells from treated tumor... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunocytochemistry (ICC/IF)
          F4/80 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry, Immunohistochemistry (Paraffin) (IHC, IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry, Immunohistochemistry (Paraffin) (IHC, IHC (P))
          F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          F4/80 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          F4/80 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Immunohistochemistry (IHC)
          F4/80 Antibody in Flow Cytometry (Flow)
          F4/80 Antibody in Flow Cytometry (Flow)
          F4/80 Antibody

          Product Details

          MF48000

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          -
          View 44 publications 44 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          -
          View 19 publications 19 publications

          Immunohistochemistry (Frozen) (IHC (F))

          -
          View 6 publications 6 publications

          Immunocytochemistry (ICC/IF)

          -
          View 5 publications 5 publications

          Flow Cytometry (Flow)

          Assay-dependent
          View 22 publications 22 publications

          Miscellaneous PubMed (MISC)

          -
          View 20 publications 20 publications
          Product Specifications

          Species Reactivity

          Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rat / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          BM8

          Immunogen

          mouse F4/80 which is a macrophage-restricted cell surface glycoprotein.

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • Alexa Fluor 488 
          • Alexa Fluor 647 
          • APC 
          • Pacific Blue
          • Pacific Orange
          • PE 
          • PE-Texas Red
          • Request custom conjugation

          Form

          Liquid

          Purification

          purified

          Storage buffer

          PBS

          Contains

          0.1% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10376289

          Target Information

          F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; lymphocyte antigen 71

          View more View less

          Gene Aliases: Adgre1; DD7A5-7; EGF-TM7; Emr1; F4/80; Gpf480; Ly71; TM7LN3

          View more View less

          UniProt ID: (Mouse) Q61549

          View more View less

          Entrez Gene ID: (Mouse) 13733

          View more View less

          Function(s)
          signal transducer activity transmembrane signaling receptor activity G-protein coupled receptor activity calcium ion binding
          Process(es)
          signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-845544bffd-2w6sl:80/100.66.135.11:80.
          git-commit: 2bb44be0f35b85de1c1d8e4f377b85e7a3a71488
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.32.0-2025.07.28-1.0