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FA2H Antibody (PA5-109704) in WB
Western blot analysis of FA2H in extracts of various cell lines. Samples were incubated with FA2H Polyclonal antibody (Product # PA5-109704) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
Product Details
PA5-109704
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 95-170 of human FA2H (NP_077282.3).
Conjugate
Form
Liquid
Concentration
0.12 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855115
Product Specific Information
Immunogen sequence: NEPVALEETQ KTDPAMEPRF KVVDWDKDLV DWRKPLLWQV GHLGEKYDEW VHQPVTRPIR LFHSDLIEGL SKTVWY
Target Information
FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; Fatty acid hydroxylase domain-containing protein 1; FLJ25287; spastic paraplegia 35 (autosomal recessive); WD repeat domain 59
Gene Aliases: FA2H; FAAH; FAH1; FAXDC1; RGD1310347; SCS7; SPG35; Wdr59
UniProt ID: (Human) Q7L5A8, (Rat) Q2LAM0
Entrez Gene ID: (Human) 79152, (Rat) 307855
sebaceous gland cell differentiation
fatty acid metabolic process
fatty acid biosynthetic process
sphingolipid biosynthetic process
lipid modification
central nervous system myelin maintenance
peripheral nervous system myelin maintenance
regulation of cell proliferation
regulation of hair cycle
oxidation-reduction process
sphingolipid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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