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Proteintech
FAF1 Polyclonal Antibody
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Product Details
10271-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FAF1 Fusion Protein Ag0407 (268-489 aa encoded by BC004970)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RSSPAQTRE QSEEQITDVH MVSDSDGDDF EDATEFGVDD GEVFGMASSA LRKSPMMPEN AENEGDALLQ FTAEFSSRYG DCHPVFFIGS LEAAFQEAFY VKARDRKLLA IYLHHDESVL TNVFCSQMLC AESIVSYLSQ NFITWAWDLT KDSNRARFLT MCNRHFGSVV AQTIRTQKTD QFPLFLIIMG KRSSNEVLNV IQGNTTVDEL MMRLMAAMEI FTA (268-489 aa encoded by BC004970)
Target Information
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A
Gene Aliases: AA408698; CGI-03; Dffrx; FAF1; Fam; hFAF1; HFAF1s; UBXD12; UBXN3A
UniProt ID: (Human) Q9UNN5, (Mouse) P54731, (Rat) Q924K2
Entrez Gene ID: (Human) 11124, (Mouse) 14084, (Rat) 140657
apoptotic process
cytoplasmic sequestering of NF-kappaB
cell death
positive regulation of cell death
regulation of cell adhesion
positive regulation of protein complex assembly
regulation of protein catabolic process
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of protein kinase activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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