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FIGURE: 1 / 1
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leadsto the disorderknown as ataxia telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitzsyndrome are also associatedwith defectsin chromosome 11. The FAM111A gene product has been provisionally designated FAM111A pending furthercharacterization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: family with sequence similarity 111, member A; protein FAM111A; Serine protease FAM111A
Gene Aliases: 4632417K18Rik; AW413625; FAM111A; GCLEB; KCS2; KIAA1895; RGD1560913
UniProt ID: (Human) Q96PZ2, (Mouse) Q9D2L9
Entrez Gene ID: (Human) 63901, (Mouse) 107373, (Rat) 499322
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