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Product Details
PA5-113059
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Protein FAM122B protein (2-247AA)
Conjugate
Form
Liquid
Concentration
2.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867793
Target Information
FAM122B (Family with Sequence Similarity 122 Member B) is a gene located on chromosome 9 that encodes a protein involved in cellular signaling and regulation. FAM122B is known to interact with protein phosphatase 2A (PP2A), a critical enzyme in multiple signaling pathways, thereby impacting various cellular functions such as growth, division, and apoptosis. This interaction is pivotal for the modulation of PP2A activity, which in turn influences numerous downstream signaling processes. Studies have indicated that FAM122B may play a role in cancer biology, particularly in the regulation of oncogenic pathways. Dysregulation of FAM122B expression has been observed in certain cancers, suggesting its potential involvement in tumor progression and as a biomarker for diagnosis or prognosis. Furthermore, the gene's expression patterns indicate its importance in normal cellular homeostasis and the maintenance of cellular signaling balance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: erg-3; ets-related; p55; PABIR family member 2; protein FAM122B; RP11-308B5.5; synoviocyte proliferation associated in collagen-induced arthritis 2; TMPRSS2/ERG fusion
Gene Aliases: 4632404H22Rik; AI256344; FAM122B; PABIR2; SPACIA2
UniProt ID: (Human) Q7Z309, (Mouse) Q6NZE7
Entrez Gene ID: (Human) 159090, (Mouse) 78755
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