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Invitrogen
FAM173B Polyclonal Antibody
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FIGURE: 1 / 1
FAM173B Antibody (PA5-121095) in WB
Western blot analysis of FAM173B in extracts of various cell lines. Samples were incubated with FAM173B Polyclonal antibody (Product # PA5-121095) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-121095
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2).
Conjugate
Form
Liquid
Concentration
1.24 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914667
Product Specific Information
Positive test controls include: A-549, BT-474, HL-60, Mouse liver, Mouse kidney, Mouse heart, Rat brain. The target is usually found in the following locations: Membrane, Single-pass membrane protein.
Immunogen sequence: MEGGGGIPLE TLKEESQSRH VLPASFEVNS LQKSNWGFLL TGLVGGTLVA VYAVATPFVT PALRKVCLPF VPATTKQIEN VVKMLRCRRG SLVDIGSGDG RIVIAAAKKG FTAVGYELNP WLVWYSRYRA WREGVHGSAK FYISDLWKVT FSQYSNVVIF GVPQMMLQLE KKLERELEDD ARVIACRFPF PHWTPDHVTG EGIDTVWAYD ASTFRGREKR PCTSMHFQLP IQA
Target Information
FAM173B is a 233 amino acid single-pass membrane protein that is encoded by a gene that maps to human chromosome 5, which makes up about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP synthase subunit C lysine N-methyltransferase; family with sequence similarity 173, member B; hFAM173B; mFam173b; protein FAM173B; Protein N-lysine methyltransferase FAM173B
Gene Aliases: A930016P21Rik; AA987072; ATPSCKMT; FAM173B; JS-2; RGD1560629
UniProt ID: (Human) Q6P4H8, (Mouse) Q9D1Z3, (Rat) D3ZLY0
Entrez Gene ID: (Human) 134145, (Mouse) 68073, (Rat) 499561
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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