Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
FAM213A Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-52640
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAM213A. Recombinant protein control fragment (Product #RP-90168).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2641376
Product Specific Information
Immunogen sequence: NTDVFLSKPQ KAALEYLEDI DLKTLEKEPR TFKAKELWEK NGAVIMAVRR PGCFLCREEA ADLSSLKSML DQLGVPLYAV VKEHIRTEVK DFQPYFKGE
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
Target Information
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: family with sequence similarity 213, member A; peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes; Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; Peroxiredoxin-like 2A; Protein PAMM; Redox-regulatory protein FAM213A; redox-regulatory protein PAMM; Sperm head protein 1; UPF0765 protein C10orf58; UPF0765 protein C10orf58 homolog
Gene Aliases: C10orf58; FAM213A; PAMM; PRO2290; PRXL2A; PSEC0139; Shp1; UNQ611/PRO1198
UniProt ID: (Human) Q9BRX8, (Rat) Q6AXX6
Entrez Gene ID: (Human) 84293, (Rat) 361118
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support