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Invitrogen
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Immunogen sequence: DSETIRLPYE EGELLEYLDA EELPPILVDL LEKSQVNIFH CGCVIAEIRD YRQSSNMKSP GYQSRHILLR PTMQTLICDV HSITSDNHKW TQED
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bA421P11.4; family with sequence similarity 48, member A; p38-interacting protein; p38IP; protein FAM48A; suppressor of Ty 20 homolog; transcription factor (p38 interacting protein); Transcription factor SPT20 homolog; tumor rejection antigen
Gene Aliases: C13; C13orf19; FAM48A; FP757; P38IP; SPT20; SUPT20H
UniProt ID: (Human) Q8NEM7
Entrez Gene ID: (Human) 55578
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