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Invitrogen
FAM62B Polyclonal Antibody
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FIGURE: 1 / 1
FAM62B Antibody (PA5-109710) in WB
Western blot analysis of FAM62B in extracts of various cell lines. Samples were incubated with FAM62B Polyclonal antibody (Product # PA5-109710) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-109710
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855121
Product Specific Information
Immunogen sequence: EKRERPPDHQ HSAQVKRPSV SKEGRKTSIK SHMSGSPGPG GSNTAPSTPV IGGSDKPGME EKAQPPEAGP QGLHDLGRSS SSLLASPGHI SVKEPTPSIA SDISLPIATQ ELRQRLRQLE NGTTLGQSPL G
Target Information
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chr2 synaptotagmin; Chr2Syt; E-Syt2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; Extended synaptotagmin-2; extended synaptotagmin-like protein 2; family with sequence similarity 62 (C2 domain containing), member B; family with sequence similarity 62, member B
Gene Aliases: 2410017M09Rik; 4921504I16Rik; CHR2SYT; D12Ertd551e; E-Syt2; ESYT2; FAM62B; KIAA1228
UniProt ID: (Human) A0FGR8, (Mouse) Q3TZZ7
Entrez Gene ID: (Human) 57488, (Mouse) 52635
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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