Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
FAM62B Monoclonal Antibody (1E10)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
H00057488-M05
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1E10
Immunogen
FAM62B (AAH13957, 1 a.a. approximately 358 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSVGHKAQES KIRYKTNEPV WEENFTFFIH NPKRQDLEVE VRDEQHQCSL GNLKVPLSQL LTSEDMTVSQ RFQLSNSGPN STIKMKIALR VLHLEKRERP PDHQHSAQVK RPSVSKEGRK TSIKSHMSGS PGPGGSNTAP STPVIGGSDK PGMEEKAQPP EAGPQGLHDL GRSSSSLLAS PGHISVKEPT PSIASDISLP IATQELRQRL RQLENGTTLG QSPLGQIQLT IRHSSQRNKL IVVVHACRNL IAFSEDGSDP YVRMYLLPDK RRSGRRKTHV SKKTLNPVFD QSFDFSVSLP EVQRRTLDVA VKNSGGFLSK DKGLLGKVLV ALASEELAKG WTQWYDLTED GTRPQAMT
Target Information
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: chr2 synaptotagmin; Chr2Syt; E-Syt2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; Extended synaptotagmin-2; extended synaptotagmin-like protein 2; family with sequence similarity 62 (C2 domain containing), member B
Gene Aliases: CHR2SYT; E-Syt2; ESYT2; FAM62B; KIAA1228
UniProt ID: (Human) A0FGR8
Entrez Gene ID: (Human) 57488
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support