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Invitrogen
FAM65A Polyclonal Antibody
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Product Details
PA5-52228
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAM65A. Recombinant protein control fragment (Product #RP-100912).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2641441
Product Specific Information
Immunogen sequence: HALESFSFLN EDEDEDNDVP GDRPPSSPEA GAEDSIDSPS ARPLSTGCPA LDAALVRHLY HCSRLLLKLG TFGPLRCQEA WALERLLREA RVLEAVCEFS RRWEIPASSA QEVVQFS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
Target Information
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 65, member A; FLJ13725; Rho family-interacting cell polarization regulator 1
Gene Aliases: FAM65A; KIAA1930; RIPOR1
UniProt ID: (Human) Q6ZS17
Entrez Gene ID: (Human) 79567
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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