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FAM65B Polyclonal Antibody

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FAM65B Antibody (17015-1-AP) in WB

Human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17015-1-AP (FAM65B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Product Details

17015-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FAM65B Fusion Protein Ag9991 (205-591 aa encoded by BC001232)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to the isoform of 119 kDa of FAM65B.

Immunogen sequence: SIKMKGLAG FARLCPGDQY EIFMKYGRQR WKLKGKIEVN GKQSWDGEET VFLPLIVGFI SIKVTELKGL ATHILVGSVT CETKELFAAR PQVVAVDIND LGTIKLNLEI TWYPFDVEDM TASSGAGNKA AALQRRMSMY SQGTPETPTF KDHSFFSNLP DDIFENGKAA EEKMPLSLSF SDLPNGDCAL TSHSTGSPSN STNPEITITP AEFNLSSLAS QNEGMDDTSS ASSRNSLGEG QEPKSHLKEE DPEEPRKPAS APSEACRRQS SGAGAEHLFL ENDVAEALLQ ESEEASELKP VELDTSEGNI TKQLVKRLTS AEVPMATDRL LSEGSVGGES EGCRSFLDGS LEDAFNGLLL ALEPHKEQYK EFQDLNQEVM NLDDILKK (205-591 aa encoded by BC001232)

Target Information

Required for hearing (PubMed:24958875). Involved in skeletal muscle development (PubMed:24687993).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.

Journal of cell science

Gao K,Tang W,Li Y,Zhang P,Wang D,Yu L,Wang C,Wu D

Sun Mar 01 00:00:00 UTC 2015

Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.

Journal of cell science

Gao K,Tang W,Li Y,Zhang P,Wang D,Yu L,Wang C,Wu D

Sun Mar 01 00:00:00 UTC 2015

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.

Proceedings of the National Academy of Sciences of the United States of America

Diaz-Horta O,Subasioglu-Uzak A,Grati M,DeSmidt A,Foster J,Cao L,Bademci G,Tokgoz-Yilmaz S,Duman D,Cengiz FB,Abad C,Mittal R,Blanton S,Liu XZ,Farooq A,Walz K,Lu Z,Tekin M

Tue Jul 08 00:00:00 UTC 2014

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.

Proceedings of the National Academy of Sciences of the United States of America

Diaz-Horta O,Subasioglu-Uzak A,Grati M,DeSmidt A,Foster J,Cao L,Bademci G,Tokgoz-Yilmaz S,Duman D,Cengiz FB,Abad C,Mittal R,Blanton S,Liu XZ,Farooq A,Walz K,Lu Z,Tekin M

Tue Jul 08 00:00:00 UTC 2014

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.

Proceedings of the National Academy of Sciences of the United States of America

Diaz-Horta O,Subasioglu-Uzak A,Grati M,DeSmidt A,Foster J,Cao L,Bademci G,Tokgoz-Yilmaz S,Duman D,Cengiz FB,Abad C,Mittal R,Blanton S,Liu XZ,Farooq A,Walz K,Lu Z,Tekin M

Tue Jul 08 00:00:00 UTC 2014

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.

Proceedings of the National Academy of Sciences of the United States of America

Diaz-Horta O,Subasioglu-Uzak A,Grati M,DeSmidt A,Foster J,Cao L,Bademci G,Tokgoz-Yilmaz S,Duman D,Cengiz FB,Abad C,Mittal R,Blanton S,Liu XZ,Farooq A,Walz K,Lu Z,Tekin M

Tue Jul 08 00:00:00 UTC 2014

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Balasubramanian A,Kawahara G,Gupta VA,Rozkalne A,Beauvais A,Kunkel LM,Gussoni E

Tue Jul 01 00:00:00 UTC 2014

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Balasubramanian A,Kawahara G,Gupta VA,Rozkalne A,Beauvais A,Kunkel LM,Gussoni E

Tue Jul 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: family with sequence similarity 65, member B; myogenesis-related and NCAM-associated protein homolog; protein FAM65B; Rho family-interacting cell polarization regulator 2

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Gene Aliases: Ab2-162; C6orf32; DFNB104; DIFF40; DIFF48; FAM65B; KIAA0386; MYONAP; PL48; RGD1306939; RIPOR2

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UniProt ID: (Human) Q9Y4F9, (Rat) Q7TP54, (Mouse) Q80U16

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Entrez Gene ID: (Human) 9750, (Rat) 306934, (Mouse) 193385

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Function(s)

protein binding ferric iron binding

Process(es)

cellular iron ion homeostasis sensory perception of sound skeletal muscle fiber development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FAM65B Polyclonal Antibody

FAM65B Antibody (17015-1-AP) in WB

Product Details

17015-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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