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Product Details
PA5-113382
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Cytosolic iron-sulfur assembly component 2A protein (1-160AA)
Conjugate
Form
Liquid
Concentration
4 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2868115
Target Information
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytosolic iron-sulfur assembly component 2A; family with sequence similarity 96, member A; MIP18 family protein FAM96A
Gene Aliases: 5730536A07Rik; CIA2A; CIAO2A; FAM96A
UniProt ID: (Human) Q9H5X1, (Mouse) Q9DCL2
Entrez Gene ID: (Human) 84191, (Mouse) 68250
Performance Guarantee
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