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Immunogen sequence: LATLIGLCLRV KLQRCLPFKH KLEIYISEGT HSTEEDINKQ INDKERVAAA
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytosolic iron-sulfur assembly component 2A; family with sequence similarity 96, member A; MIP18 family protein FAM96A
Gene Aliases: CIA2A; CIAO2A; FAM96A
UniProt ID: (Human) Q9H5X1
Entrez Gene ID: (Human) 84191
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