Proteintech

FAM96B Polyclonal Antibody

FAM96B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

FAM96B Antibody (20108-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney using 20108-1-AP (FAM96B antibody) at dilution of 1:100 (under 40x lens).

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Product Details

20108-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FAM96B Fusion Protein Ag13827 (1-163 aa encoded by BC001733)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MVGGGGVGG GLLENANPLI YQRSGERPVT AGEEDEQVPD SIDAREIFDL IRSINDPEHP LTLEELNVVE QVRVQVSDPE STVAVAFTPT IPHCSMATLI GLSIKVKLLR SLPQRFKMDV HITPGTHASE HAVNKQLADK ERVAAALENT HLLEVVNQCL SARS (1-163 aa encoded by BC001733)

Target Information

Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The FAM96B gene product has been provisionally designated FAM96B pending further characterization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.

The Journal of biological chemistry

Fan X,Barshop WD,Vashisht AA,Pandey V,Leal S,Rayatpisheh S,Jami-Alahmadi Y,Sha J,Wohlschlegel JA

Fri Jul 01 00:00:00 UTC 2022

The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2.

Communications biology

Mariotti L,Wild S,Brunoldi G,Piceni A,Ceppi I,Kummer S,Lutz RE,Cejka P,Gari K

Tue Jun 23 00:00:00 UTC 2020

Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.

Nature structural & molecular biology

Naseri NN,Ergel B,Kharel P,Na Y,Huang Q,Huang R,Dolzhanskaya N,Burré J,Velinov MT,Sharma M

Sat Feb 01 00:00:00 UTC 2020

An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis.

Molecular cell

Mayank AK,Pandey V,Vashisht AA,Barshop WD,Rayatpisheh S,Sharma T,Haque T,Powers DN,Wohlschlegel JA

Thu Jul 25 00:00:00 UTC 2019

The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins.

Cell reports

Odermatt DC,Gari K

Tue Feb 07 00:00:00 UTC 2017

The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins.

Cell reports

Odermatt DC,Gari K

Tue Feb 07 00:00:00 UTC 2017

The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

The Journal of biological chemistry

Vashisht AA,Yu CC,Sharma T,Ro K,Wohlschlegel JA

Fri May 29 00:00:00 UTC 2015

The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

The Journal of biological chemistry

Vashisht AA,Yu CC,Sharma T,Ro K,Wohlschlegel JA

Fri May 29 00:00:00 UTC 2015

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

Cell metabolism

Stehling O,Mascarenhas J,Vashisht AA,Sheftel AD,Niggemeyer B,Rösser R,Pierik AJ,Wohlschlegel JA,Lill R

Tue Aug 06 00:00:00 UTC 2013

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

Cell metabolism

Stehling O,Mascarenhas J,Vashisht AA,Sheftel AD,Niggemeyer B,Rösser R,Pierik AJ,Wohlschlegel JA,Lill R

Tue Aug 06 00:00:00 UTC 2013

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.

Science (New York, N.Y.)

Stehling O,Vashisht AA,Mascarenhas J,Jonsson ZO,Sharma T,Netz DJ,Pierik AJ,Wohlschlegel JA,Lill R

Fri Jul 13 00:00:00 UTC 2012

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.

Science (New York, N.Y.)

Stehling O,Vashisht AA,Mascarenhas J,Jonsson ZO,Sharma T,Netz DJ,Pierik AJ,Wohlschlegel JA,Lill R

Fri Jul 13 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Cytosolic iron-sulfur assembly component 2B; family with sequence similarity 96, member B; Mitotic spindle-associated MMXD complex subunit MIP18; MSS19-interacting protein of 18 kDa; Protein FAM96B

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Gene Aliases: CGI-128; CIAB; CIAO2B; FAM96B; HSPC118; MIP18

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UniProt ID: (Human) Q9Y3D0

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Entrez Gene ID: (Human) 51647

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Function(s)

protein binding

Process(es)

chromosome segregation iron-sulfur cluster assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FAM96B Polyclonal Antibody

FAM96B Antibody (20108-1-AP) in IHC (P)

Product Details

20108-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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